| Episode | Name | Airdate |
|---|
| S04E01 | Hugh Jackman, Shay Mitchell | oct. 5, 2015 |
| S04E02 | Sarah Michelle Gellar, Shaquille O'Neal | oct. 6, 2015 |
| S04E03 | Rooney Mara, Gina Rodriguez, Abby Wambach | oct. 7, 2015 |
| S04E04 | Seth Rogen, Billy Eichner, the Vamps | oct. 8, 2015 |
| S04E05 | Kate Winslet, Ted Danson, Sara Bareilles | oct. 9, 2015 |
| S04E06 | Clive Owen, Jussie Smollett, Ronda Rousey | oct. 12, 2015 |
| S04E07 | Jessica Chastain, Gabrielle Union, guest co-host Ciara | oct. 13, 2015 |
| S04E08 | Tom Hanks, Carey Mulligan | oct. 14, 2015 |
| S04E09 | Tom Selleck, Jennifer Carpenter, Andra Day | oct. 15, 2015 |
| S04E10 | Jack Black, Amy Brenneman | oct. 16, 2015 |
| S04E11 | Jimmy Kimmel, Robin Thicke, Daniel Boulud | oct. 19, 2015 |
| S04E12 | Vin Diesel, Amanda Peet, Alfred Portale | oct. 20, 2015 |
| S04E13 | Michael J. Fox, Sarah Paulson, Alex Guarnaschelli | oct. 21, 2015 |
| S04E14 | Patricia Heaton, Ed Westwick, Marc Forgione | oct. 22, 2015 |
| S04E15 | Kate Hudson, Kat Dennings, Eric Ripert | oct. 23, 2015 |
| S04E16 | Stanley Tucci, Wesley Snipes | oct. 26, 2015 |
| S04E17 | Adam Levine, Mike Tyson | oct. 27, 2015 |
| S04E18 | Seth Meyers, Stephen Moyer, Andrea Bocelli | oct. 28, 2015 |
| S04E19 | Sandra Bullock, Jamie Oliver | oct. 29, 2015 |
| S04E20 | LIVE's Best Halloween Show Ever: Nightmare on 67th Street | oct. 30, 2015 |
| S04E21 | Allison Janney, Steve Martin & Edie Brickell, Andrea Arden | nov. 2, 2015 |
| S04E22 | Gwen Stefani, Ralph Fiennes, Dr. Jennifer Jellison | nov. 3, 2015 |
| S04E23 | Andy Cohen, Bryan Adams, Dr. Karen Halligan | nov. 4, 2015 |
| S04E24 | Daniel Craig, Harry Connick Jr., Bernadette Peters | nov. 5, 2015 |
| S04E25 | Christoph Waltz, Antonio Banderas | nov. 6, 2015 |
| S04E26 | Daniel Radcliffe; Bryshere Gray; Seal | nov. 9, 2015 |
| S04E27 | Jennifer Connelly, Rainn Wilson, James Bay | nov. 10, 2015 |
| S04E28 | Viola Davis, James McAvoy | nov. 11, 2015 |
| S04E29 | Ethan Hawke, Emma Roberts, Tim McGraw | nov. 12, 2015 |
| S04E30 | John Stamos, Dr. Melina Jampolis explains the Doctor on Demand Diet, A Great Big World | nov. 13, 2015 |
| S04E31 | Blake Shelton, Kyle Chandler, Kelly and Michael taste-test fast-food fries | nov. 16, 2015 |
| S04E32 | Cate Blanchett, Burt Reynolds, Katie Brown teaches Kelly and Michael how to wrap gifts | nov. 17, 2015 |
| S04E33 | Liam Hemsworth, CeeLo Green, Kelly and Michael host the entire show while dressed in their pajamas | nov. 18, 2015 |
| S04E34 | Hillary Clinton, Josh Hutcherson, musical duo A Great Big World teaches Kelly and Michael how to write a song | nov. 19, 2015 |
| S04E35 | Elizabeth Banks, Shawn Mendes, Kelly and Michael stomp grapes | nov. 20, 2015 |
| S04E36 | Pharrell Williams, Jena Malone, Holly Holm | nov. 23, 2015 |
| S04E37 | Jennifer Hudson, Josh Groban | nov. 24, 2015 |
| S04E38 | Mariah Carey, Melissa Benoist, Kyle Busch | nov. 25, 2015 |
| S04E39 | Jesse Tyler Ferguson, Beth Behrs, Joss Stone, Carly Simon | nov. 27, 2015 |
| S04E40 | Michael Chiklis, Uzo Aduba, Michelle Tan | nov. 30, 2015 |
| S04E41 | Harrison Ford, Frank Grillo, Monica Mangin | déc. 1, 2015 |
| S04E42 | Mary J. Blige, Faith Ford, Ted McGinley, Lance Ulanoff | déc. 2, 2015 |
| S04E43 | Carrie Fisher, Chris Byrne | déc. 3, 2015 |
| S04E44 | Justin Theroux, Lawrence Zarian | déc. 4, 2015 |
| S04E45 | Chris Hemsworth, Billie Lourd | déc. 7, 2015 |
| S04E46 | Maya Rudolph, Daisy Ridley, Gigi Hadid | déc. 8, 2015 |
| S04E47 | Donald Trump, John Boyega, Chris Isaak | déc. 9, 2015 |
| S04E48 | Amy Poehler, Mandy Patinkin | déc. 10, 2015 |
| S04E49 | Lupita Nyong'o, Kirsten Dunst | déc. 11, 2015 |
| S04E50 | Mark Wahlberg, Gwendoline Christie, Sara Bareilles | déc. 14, 2015 |
| S04E51 | Jennifer Lawrence, Raymond Crowe | déc. 15, 2015 |
| S04E52 | Will Ferrell, Bella Thorne | déc. 16, 2015 |
| S04E53 | Kurt Russell, Daya | déc. 17, 2015 |
| S04E54 | Kurt Russell, Daya | déc. 18, 2015 |
| S04E55 | Bruce Willis, Kevin Zraly, a performance from "Disney On Ice: 100 Years Of Magic" | déc. 21, 2015 |
| S04E56 | Channing Tatum, Cee-Lo Green, the Rockettes | déc. 22, 2015 |
| S04E57 | Adam Levine, Jack Black, Ronda Rousey, Trevor Noah | déc. 23, 2015 |
| S04E58 | Carol Burnett, Ariana Grande, Jussie Smollett, Stephen Curry | déc. 24, 2015 |
| S04E59 | Samuel L. Jackson, Ben Higgins, Miss Universe Pia Wurtzbach | janv. 4, 2016 |
| S04E60 | Ryan Seacrest, Jennifer Jason Leigh | janv. 5, 2016 |
| S04E61 | Felicity Huffman, Damian Lewis, James Oseland | janv. 6, 2016 |
| S04E62 | Emmy Rossum, Shaun T | janv. 7, 2016 |
| S04E63 | Tyler Perry, Dr. Ian Smith | janv. 8, 2016 |
| S04E64 | John Krasinski, Heather Graham | janv. 11, 2016 |
| S04E65 | Ray Liotta, Lucy Hale | janv. 12, 2016 |
| S04E66 | Ice Cube, Brie Larson, Jason Jacobson | janv. 13, 2016 |
| S04E67 | Olivia Munn | janv. 14, 2016 |
| S04E68 | Khloe Kardashian, desert animals from the San Diego Zoo | janv. 15, 2016 |
| S04E84 | Katie Holmes, Vanna White | févr. 8, 2016 |
| S04E85 | Ryan Reynolds, Fred Savage | févr. 9, 2016 |
| S04E86 | Ben Stiller, Bob Odenkirk | févr. 10, 2016 |
| S04E87 | Penelope Cruz, Bobby Cannavale, Maddie & Tae | févr. 11, 2016 |
| S04E88 | A celebration of Kelly's 15th anniversary as co-host | févr. 12, 2016 |
| S04E89 | Allison Williams, Danai Gurira, Rick Springfield | févr. 15, 2016 |
| S04E90 | Lena Dunham, Jeff Probst | févr. 16, 2016 |
| S04E91 | Anthony Anderson, Derek Hough, Lance Ulanoff | févr. 17, 2016 |
| S04E92 | Kiefer Sutherland, Travis Fimmel, Jazmine Sullivan | févr. 18, 2016 |
| S04E93 | Jeremy Irons, Lori Loughlin, Chris Byrne | févr. 19, 2016 |
| S04E154 | Chris O'Donnell, Cedric the Entertainer, Trent Harmon | avr. 11, 2016 |
| S04E155 | Gwyneth Paltrow, Jennifer Arnold and Bill Klein, La'Porsha Renae | avr. 12, 2016 |
| S04E156 | Kevin Costner, Ken Jeong, Dalton Rapattoni | avr. 13, 2016 |
| S04E157 | Lupita Nyong'o, Regina Hall | avr. 14, 2016 |
| S04E158 | Common, Saoirse Ronan | avr. 15, 2016 |
| S04E159 | Katharine McPhee, Terry Crews, Amy E. Goodman | avr. 18, 2016 |
| S04E160 | Jason Bateman, Dr. Melinda Jampolis | avr. 19, 2016 |
| S04E161 | Von Miller, Witney Carson, Dr. Taz Bhatia | avr. 20, 2016 |
| S04E162 | Daniel Dae Kim | avr. 21, 2016 |
| S04E163 | Julia Louis-Dreyfus, Dr. David Agus | avr. 22, 2016 |
| S04E164 | Guest Co-Hostess Shay Mitchell, Donnie Wahlberg, Tim Daly | avr. 25, 2016 |
| S04E165 | Bellamy Young, Jaimie Alexander, Jackie Evancho | avr. 26, 2016 |
| S04E166 | Ricky Gervais, Josh Hartnett | avr. 27, 2016 |
| S04E167 | Kate Hudson, Keegan-Michael Key, Peter Gros | avr. 28, 2016 |
| S04E168 | Adam Levine, Jordan Peele | avr. 29, 2016 |
| S04E169 | Adrien Brody, Chadwick Boseman, Ruth B | mai 2, 2016 |
| S04E170 | Lucy Liu, Morris Chestnut | mai 3, 2016 |
| S04E171 | Jeremy Renner, Carrie Ann Inaba | mai 4, 2016 |
| S04E172 | Robert Downey Jr., Jason Derulo, Marcela Valladoid | mai 5, 2016 |
| S04E173 | Anthony Mackie | mai 6, 2016 |
| S04E174 | Jodie Foster, Megyn Kelly | mai 9, 2016 |
| S04E175 | Jessica Lange, Laura Bush, Jenna Bush Hager | mai 10, 2016 |
| S04E176 | Chelsea Handler, Lana Parrilla | mai 11, 2016 |
| S04E177 | Kate Beckinsale, Joe Morton, Kelsea Ballerini | mai 12, 2016 |
| S04E178 | Matt Bomer, Carmelo Anthony | mai 13, 2016 |
